Publication |
2012.
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Summary/Abstract |
Rapid public health response to a large-scale anthrax attack would reduce overall morbidity and mortality. However there is uncertainty about the optimal cost effective response strategy based on timing of intervention, public health, resources, and critical care facilities. We connected a decision analytic study to compare response strategies to a theoretical large scale anthrax attack on the Chicago metropolitan area beginning either Day 2 or Day 5 after the attack. These strategies correspond to the policy option set forth by the Anthrax Modeling Working Group for population-wide response to a large scale anthrax attack: (1) postattack antibiotic prophylaxix, (2) postattack antibiotic prophylaxis and vaccination, (3) Preattack vaccination with postattack antibiotic prophylaxis, and (4) preattack vaccination with postattack antibiotic prophylaxis and vaccination.
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