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ID:
149011
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| Summary/Abstract |
Anthrax, caused by Bacillus anthracis is known to occur globally since antiquity. Besides being an important biothreat agent, it is an important public health importance pathogen also in countries like India. B. anthracis secretes three distinct toxins, namely protective antigen (PA), lethal factor (LF) and edema factor (EF). PA is the central moiety of the anthrax toxin complex and therefore has been a molecule of choice for vaccine development. PA has four different domains with different functions. In this study, the major domains of PA were cloned and expressed in bacterial system. The purified recombinant proteins were used to determine the humoral immune response by ELISA using 43 human cutaneous anthrax serum samples. The maximum immunoreactivity was observed with the whole PA protein followed by domain 2, 4 and 1. The study corroborated that in addition to full PA, individual domain 2 and 4 can also be good target for vaccine development as well as for serodiagnostic assays for cutaneous anthrax
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| 2 |
ID:
171075
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| Summary/Abstract |
This study examines the nexus between the defense spending growth rate and inflation to test whether defense spending is inflationary in China, particularly in times of peace. Using wavelet analysis, we find that the linkage between the defense spending growth rate and inflation changes over time and across frequencies. We provide evidence supporting negative leading effects of inflation on the defense spending growth rate in certain periods across various frequencies. The results illustrate that the relationship is stronger at the short- to medium-term horizon of less than eight years than it is in the long term. No positive leading effect of defense spending on inflation is demonstrated, showing that defense spending is not inflationary in China. The results indicate that inflation lowers the defense spending growth rate at short and medium scales, particularly in peace time. This study provides new insights into the nexus between defense spending and inflation and emphasizes that such a correlation has time and frequency features. Meanwhile, given that there is little evidence supporting the idea that defense spending is inflationary, a moderate increase in defense spending will not damage price stability in China.
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| 3 |
ID:
108292
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